人正常前列腺基質永生化細胞WPMY-1
| ??【編號】：WPMY-1 ??【名稱】：人正常前列腺基質永生化細胞WPMY-1 ??【規格】：株 ??【價格】：2300   人正常前列腺基質永生化細胞
細胞名稱：WPMY-1人正常前列腺基質永生化細胞
描述：肌成纖維基質細胞株, WPMY-1, 與RWPE-1 cells (ATCC CRL-11609)一樣，來源于同一張成人前列腺組織切片的周圍區域的基質細胞。 通過一個pRSTV質料結構，用SV40大T抗原對基質細胞進行永生化。 WPMY-1細胞，與RWPE-1細胞及其它上皮細胞衍生株一樣，屬于來源于同一個前列腺的一系列細胞株。 由于它們來源于同一個前列腺的周圍區域，WPMY-1細胞株對于研究分泌和基質與上皮細胞相互作用尤其有用。 據提供者報道，來源于同一個前列腺的RWPE-1細胞株(ATCC CRL-11609)，經過檢測，乙肝、丙肝、人免疫缺陷病毒都呈陰性。
種別：人
性別：男
組織來源：器官： 前列腺 組織： 基質 疾病： 正常
形態：成肌細胞
培養基和添加劑：DMEM培養基(GIBCO,貨號12800017，添加NaHCO3 1.5g/L)，95%；優質胎牛血清，5%。 氣相：空氣，95%；二氧化碳，5%。 溫度：37攝氏度。
供應限制：A。僅供研究之用。
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Cadmium induces c-myc, p53, and c-jun expression in normal human prostate epithelial cells as a prelude to apoptosis. Toxicol. Appl. Pharmacol. 164: 291-300, 2000. PubMed: 10799339 53194: Achanzar WE, et al. Cadmium-induced malignant transformation of human prostate epithelial cells. Cancer Res. 61: 455-458, 2001. PubMed: 11212230 53196: Bello-DeOcampo D, et al. Laminin-1 and alpha6beta1 integrin regulate acinar morphogenesis of normal and malignant human prostate epithelial cells. Prostate 46: 142-153, 2001. PubMed: 11170142 53197: Webber MM, et al. Human cell lines as an in vitro/in vivo model for prostate carcinogenesis and progression. Prostate 47: 1-13, 2001. PubMed: 11304724 89996: Quader ST, et al. Evaluation of the chemopreventive potential of retinoids using a novel in vitro human prostate carcinogenesis model. Mutat. Res. 496: 153-161, 2001. PubMed: 11551491 89997: Webber MM, et al. 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Altered apoptotic gene expression and acquired apoptotic resistance in cadmium-transformed human prostate epithelial cells. Prostate 52: 236-244, 2002. PubMed: 12111698 90378: Carruba G, et al. Intercellular communication and human prostate carcinogenesis. Ann. N.Y. Acad. Sci. 963: 156-168, 2002. PubMed: 12095941 90379: Saladino F, et al. Connexin expression in nonneoplastic human prostate epithelial cells. Ann. N.Y. Acad. Sci. 963: 213-217, 2002. PubMed: 12095946 90380: Hegarty PK, et al. Effects of cyclic stretch on prostatic cells in culture. J. Urol. 168: 2291-2295, 2002. PubMed: 12394777 90383: Lugassy C, et al. Human melanoma cell migration along capillary-like structures in vitro: a new dynamic model for studying extravascular migratory metastasis. J. Invest. Dermatol. 119: 703-704, 2002. PubMed: 12230517 90384: Brambila EM, et al. Chronic arsenic-exposed human prostate epithelial cells exhibit stable arsenic tolerance: mechanistic implications of altered cellular glutathione and glutathione S-transferase. Toxicol. Appl. Pharmacol. 183: 99-107, 2002. PubMed: 12387749 90385: Achanzar WE, et al. Inorganic arsenite-induced malignant transformation of human prostate epithelial cells. J. Natl. Cancer Inst. 94: 1888-1891, 2002. PubMed: 12488483 186709: Mukta M Webber, personal communication |
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